Wait. What’s an exosome?

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Ever heard of an exosome? Let’s dig into why exosomes in skin care may be the future of skin regeneration.

Exosomes: The Small Messengers of Skin Rejuvenation

Exosomes are small extracellular vesicles that play a key role in intercellular communication. These tiny structures are released by various cell types, including stem cells, and contain a variety of molecules such as proteins, lipids, and growth factors. In the context of skin care, exosomes have emerged as a promising innovation for treating all kinds of skin conditions and contributing to overall skin health.

Understanding the Role of Exosomes

When exosomes are secreted by stem cells, they carry valuable cargo that can stimulate regeneration and repair processes in the skin. These extracellular vesicles are able to target specific cells and deliver their cargo, promoting the production of collagen, elastin, and other essential components for healthy and youthful-looking skin.

How Exosomes Work

Exosomes function by transferring their cargo, including proteins, lipids, and growth factors, to recipient cells, facilitating communication between cells and triggering regenerative processes. This cargo can direct the recipient cells to produce collagen, elastin, and other essential components for healthy skin. Through this mechanism, exosomes support skin rejuvenation by promoting regeneration, reducing inflammation, and improving overall skin health.

Growth Factors

You’ve probably heard of growth factors being used for anti-aging in skincare. Well, part of what makes exosomes so exciting is their rich growth factor content! Growth factors, such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), play a crucial role in maintaining the health and vitality of the skin as you age. When delivered through exosomes in a professional skin treatment, these growth factors can target specific skin concerns and promote the regeneration of damaged skin cells.

Overall Rejuvenating Effects

Exosomes have been found to trigger significant improvement in skin health by stimulating collagen production, improving skin texture and elasticity, and promoting a more youthful appearance. This broad range of regenerative properties and applications make exosomes an exciting prospect for those looking to combat the signs of aging, alleviate uneven skin tone or pigmentation, or heal wounds or scars.

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How are the exosomes used in skin therapies created?

Mesenchymal Stem Cell (MSC) Derived Exosomes

One of the most common sources of exosomes used in skin care products is mesenchymal stem cells (MSCs). These cells are known for their regenerative properties and their ability to secrete exosomes containing a wide range of bioactive molecules. When derived from MSCs, exosomes can be incorporated into topical creams, serums, and other products to enhance skin rejuvenation.

Mesenchymal stem cell-derived exosomes have gained significant attention in the field of skin care due to their regenerative properties. These exosomes contain different types of proteins and growth factors that can stimulate collagen production, reduce inflammation, and improve overall skin health. By harnessing the regenerative potential of mesenchymal stem cell-derived exosomes, skincare products can effectively address various signs of aging and promote a more youthful appearance.

Platelet Derived Exosomes

Another source of exosomes in skin care is platelets. Platelet-derived exosomes are rich in growth factors and other proteins that promote wound healing and tissue regeneration. These exosomes can be used in combination with other skin care treatments, such as microneedling, to enhance their regenerative effects and improve skin appearance.

Do exosomes really work?

Latest Studies on Exosomes in Skin Rejuvenation

Research on exosomes in skin care has shown promising results. Studies have demonstrated the ability of exosomes to stimulate collagen production, reduce inflammation, and enhance wound healing. Furthermore, exosomes have shown potential in addressing various skin concerns, such as pigmentation abnormalities, acne scars, and premature aging.

Advancements in Exosome Research for Skincare

Ongoing advancements in exosome research are further expanding our understanding of their role in skin rejuvenation. Scientists are uncovering new ways to optimize exosome delivery, improve their regenerative effects, and develop innovative formulations for maximal efficacy. These advancements hold great promise for the future of skin care, offering the potential for even more effective and personalized treatments.

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How are exosomes used in skin treatments?

Exosomes are starting to be used more widely in various types of skin treatments that promote skin rejuvenation. Here are just a few examples of where you might see exosomes used in skin therapies:

Exosome-Enhanced Microneedling

The injury caused by microneedling creates micro-channels that help deliver product to the deeper layers of the skin. When placed on skin after a microneedling procedure, exosomes are able to penetrate deeper into the skin and deliver more effective results. This combination treatment has shown promising results in improving skin texture and reducing the signs of aging!

Exosome-Infused Facial Serums

Skincare products, such as serums and creams, can be formulated with exosomes. These products are designed for topical application and are intended to deliver exosome-derived bioactive molecules directly to the skin’s surface.

Exosome-Containing Masks

Sheet masks and facial masks infused with exosomes aim to provide a concentrated application of exosome-derived ingredients to the skin, potentially promoting hydration, radiance, and overall skin health.

Post-Procedure Recovery

Exosomes are sometimes used after certain aesthetic procedures, such as laser treatments or chemical peels, to support the skin’s healing process.

Hair and Scalp Treatments

Exosomes are not limited to skin treatments; they are also being investigated for their potential benefits in promoting hair growth and improving overall scalp health.

Anti-Aging and Rejuvenation

Exosome-based treatments are largely marketed as solutions for reducing the appearance of wrinkles, fine lines, and age-related skin changes. They are believed to contribute to collagen production and skin regeneration, leading to more youthful skin.

Scar Reduction

Exosomes could potentially aid in the healing of wounds and scars by promoting tissue repair and regeneration. They may be used to improve the appearance of surgical scars or acne scars.

Who could benefit from exosome skin therapies?

Skincare products with exosomes could potentially benefit you if you’re looking to address specific skin concerns and promote overall skin health. Below you’ll find just a few examples of skin conditions that may benefit from treatment with exosomes.


If you’re concerned about the signs of skin aging, such as wrinkles, fine lines, and loss of skin elasticity, you might want to consider an exosome skin treatment. Exosomes could potentially promote collagen production, support skin regeneration, and improve skin texture, leading to a more youthful appearance.

Uneven Skin Tone and Pigmentation

If you’re seeking a more even complexion, exosomes may have the potential to influence skin pigmentation and address issues like hyperpigmentation and uneven skin tone.

Dry or Dehydrated Skin

Exosomes may help improve skin hydration by delivering moisture-retaining compounds to the deeper layers of the skin. If you have dry or dehydrated skin, you may find exosome-based products helpful in maintaining skin hydration.

Sensitive Skin

Because exosomes are a natural component of cell communication, they might be suitable if you have sensitive skin and are seeking gentler skincare options. Exosome-based products could potentially offer effective results without causing as much irritation or sensitization as other skincare products.

Is exosome therapy better than stem cells or PRP?

Exosome skin therapies, platelet-rich plasma (PRP), and stem cell-based treatments are all approaches used in aesthetics to promote skin health and address various skin concerns. While similar, each treatment has its own potential benefits and considerations:

Advantages of Exosome Therapy

Exosome therapy offers several unique advantages over traditional methods of skin rejuvenation. Firstly, they are derived from natural sources, reducing the risk of adverse reactions. Additionally, exosomes can penetrate the skin more effectively than larger molecules, ensuring optimal delivery of their cargo to target cells. Lastly, exosomes are highly versatile and can be combined with other active ingredients to create customized skin care formulations for specific needs.

Exosome Therapy v. Stem Cell Treatments

While stem cell treatments have shown promise in skin rejuvenation, they have certain limitations, such as the potential for immune rejection and ethical concerns. Exosome therapy overcomes these limitations by utilizing the beneficial effects of exosomes derived from stem cells without requiring the use of living cells. This allows for a safer and more ethical approach to skin rejuvenation.

Exosome Therapy v. Platelet Rich Plasma (PRP) Treatments

PRP is a trusted treatment in the field of skin rejuvenation, but it may not be for everyone. While PRP primarily relies on the growth factors released by platelets, exosomes can carry a diverse cargo of molecules, including proteins, lipids, and nucleic acids like RNA. This diverse payload can potentially exert a broader range of effects compared to PRP. Additionally, since exosomes are derived from cells, there might be a reduced risk of adverse reactions compared to treatments that involve manipulating whole cells, such as PRP. And if you aren’t a fan of needles, you may want to consider exosome therapy instead. Often delivered through topical applications or injections, exosome therapy is generally considered less invasive and more convenient than PRP, which requires a blood draw and centrifugation to separate the platelets.

It’s important to note that the benefits of each approach can vary based on your unique needs and goals. We recommend scheduling a consultation with one of our expert estheticians to help choose the treatment that’s right for you. 

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Experience the benefits of exosomes at Center Medspa.

As research on exosomes continues to expand, it is clear that they hold immense potential for revolutionizing the field of skin care and unlocking new possibilities for achieving healthier, more youthful-looking skin. CenterMedspa is excited to offer meticulously researched Benev exosomes as an add-on for several of our services: MicroneedlingVirtue RF & Exact RF Microneedling, and CoolPeel.

Schedule a consultation today to explore how exosomes could enhance your skincare journey!